Epidemiology, Microbiological Profile and Susceptibility Pattern of Uropathogens from a Tertiary Care Hospital in Central India.

• Rupam Gahlot,  
• Suchita Netam,  
• Sneha Dadarya,  
• Nikita Sherwani,  
• Shuchita Gaur*

Abstract

Background: Urinary tract infections (UTIs) are the second most common infection in the community, whereas in hospitals, they are the most common healthcare-associated infections. Monitoring factors like the most common causative organisms and their susceptibility pattern is essential for tailored management and practicing antimicrobial stewardship. This study was done to determine the epidemiology, microbiological profile, and susceptibility pattern of uropathogens to make better antibiotic policy. Methodology: This was a retrospective descriptive study done at the Department of Microbiology, Pt. JNM Medical College, Raipur, Chhattisgarh in which analysis of the culture isolates obtained from urine samples received between January 2022 to December 2022 was performed. Results: Out of 2893 urine samples,784 (27.1%) showed significant growth on culture. Females were more affected than males with male to female ratio being 1:2.3.Most common causative organism found in our study was Escherichia coli(41.9%) followed by Enterococcus species (23.9%), non-albicans Candida species(11.09%) and Klebsiella pneumoniae(10.3%).Escherichia coli isolates showed 100% susceptibility to fosfomycin; 93% for nitrofurantoin, and 93% for carbapenems. In the case of isolates of Klebsiella pneumonia, the susceptibility percentage for nitrofurantoin and carbapenems were 59% and 82% respectively. In Enterococcus species isolates were 100% susceptible to Teicoplanin and Fosfomycin, 82% for Nitrofurantoin. Conclusion: Escherichia coli followed by Enterococcus species the most common uropathogen. Nitrofurantoin and Fosfomycin were the most effective antibiotics against uropathogens.

Keywords

UTI, Urinary Tract Infection, Uropathogens, antibiogram, Microbiological profile, antimicrobial susceptibility,India