Detection of anti DENV IgM and IgG antibodies by evaluating the rapid immunochromatographic technique in hospital at Himmatnagar, Gujarat

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Original Article

Author Details : Nimisha Shethwala, Amar Shah*

Volume : 7, Issue : 2, Year : 2020

Article Page : 192-194

https://doi.org/10.18231/j.ijmr.2020.033

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Abstract

Background: Infections arising out of dengue is a prime concern in the country. Himmatnagar too is not
devoid of its devastating effects. In order to identify the existence of the virus of dengue, some serological
tests are done in the labs. The effectiveness of rapid immunochromatographic test has been accessed in this
study in identifying antibodies to Dengue virus (DENV).
Materials and Methods: In this study, the patients having the signs of infection of dengue were included
and the serum samples of such patients were obtained for the purpose. The tests of the samples were
performed with Panbio Dengue Duo Cassette for the ruling of antibodies of IgG and IgM. Further, for
antibody capture test and the detection of the same, immunochromatrgraphic testings were taken into
consideration.
Result: The exactness of index for the detection of IgG and IgM can be traced down with the results where
the sensitivity lasted with figures like 79% and 83% along with specificity having a figure of 65% and 58%
whilst the positive and negative predictive values remained 57 and 64 percent as well as 85 and 72 percent
respectively. (Decimals either contracted or rounded off).
Conclusion: The device showcased approval to DENVs in perceiving the IgG and IgM antibodies but it
cannot be suggested for confirmatory diagnostic test.

Keywords: Infection, Dengue, Virus, Antibody.

How to cite : Shethwala N, Shah A , Detection of anti DENV IgM and IgG antibodies by evaluating the rapid immunochromatographic technique in hospital at Himmatnagar, Gujarat. Indian J Microbiol Res 2020;7(2):192-194

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