Epidemiology and antimicrobial resistance pattern of Vibrio cholerae isolates at a tertiary care health laboratory

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Original Article

Author Details : Sudheendra Kulkarni*, Chandrakanth Chillarge

Volume : 7, Issue : 4, Year : 2020

Article Page : 358-361

https://doi.org/10.18231/j.ijmr.2020.064

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Abstract

Introduction: Vibrio cholerae is a common causative agent of acute diarrheal disease across the world. Significant variations in epidemiological pattern and in vitro susceptibility of isolates are commonly observed. Emerging and progressive antibiotic resistance is frequently reported.
Objective of the Study: The aim and objective of conducting the current study was; To find out the epidemiological profile of cholera cases isolated from Bidar and surrounding area. To find out the antibiotic resistance pattern of these isolated enteropathogens.
Materials and Methods: The current study was carried out at tertiary care medical centre in Bidar, Karnataka for the period of 4 years from 2012-2015. A total of 310 fecal specimens were collected from clinically symptomatic (diarrheic/dysentric) individuals. The collected fecal samples were processed for commonly isolated enteropathogens by standard bactreriological methods. The colonies suspective of V. cholera were identified by standard biochemical reactions and serological confirmation was done by using specific antisera. Kirby-bauer’s disc diffusion method in accordance with Clinical and Laboratory Standards
Institute guidelines was employed to find out the antimicrobial susceptibility profile.
Results: Out of 310 fecal samples, Vibrio cholerae biotype was isolated from 95 samples (30.64%). Among 95 isolated Vibrio cholerae strains 70 (73.68%) were belonged to serotype Ogawa, 15 to Inaba (15.78%) and 10 to Hikozima (10.52%). The isolated strains proved multi drug resistant to ampicillin and nalidixic acid and uniformly sensitive to tetracycline, ofloxacin, ciprofloxacin, chloramphenicol and gentamicin.
Conclusion: Our study revealed that, cholera cases in North Karnataka are found to be prevalent among age group of 15-25 and in females. The current study showed the importance of control and monitoring of V. cholerae by serogroup and antibiogram typing for policy makers and health professionals of this region as incidence of cholera increased year wise.

Keywords: Antibiotic susceptibility, Cholera, ElTor, Epidemic, Prevalence, Vibrio cholerae.

How to cite : Kulkarni S , Chillarge C, Epidemiology and antimicrobial resistance pattern of Vibrio cholerae isolates at a tertiary care health laboratory. Indian J Microbiol Res 2020;7(4):358-361

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