Retrospective study of bacteriological profile and their antibiotic sensitivity pattern in urine of pediatric patients (0-12 years) in a tertiary care hospital of South Gujarat

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Original Article

Author Details : Neeta Khandelwal, Dharmishtha Sutariya*

Volume : 7, Issue : 4, Year : 2020

Article Page : 373-376

https://doi.org/10.18231/j.ijmr.2020.067

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Abstract

Background & Aim: Urinary Tract Infections are common bacterial infections in pediatric age group. The diagnosis of UTI is very often missed in lower pediatric age group due to minimal and nonspecific symptoms. Etiological agents of UTI are variable and commonly depend on time, geographical location and age of patients. However E.coli and Klebsiella pneumoniae account for most of the cases. Present study aims at to determine prevalence and to evaluate changing trends of etiology and antibiogram of
urinary isolates in children of 0-12 year age group attending Tertiary care hospital, of South Gujarat.
Materials and Methods: A retrospective study was carried out in the Microbiology department of Tertiary care hospital of South Gujarat including all indoor pediatric patient’s urine samples received over duration of 6 months. Urine samples were processed according to routine protocol of the microbiology laboratory. Different bacterial isolates from urine samples were identified by using various biochemical reactions. Antibiotic-Susceptibility Testing was done using Kirby bauer disc diffusion method according to
CLSI guidelines, 2018 for particular year. Qualitative data were presented as a proportion.
Results: Total 59 samples showed bacterial growth out of 595 indoor pediatric urine samples. Gram positive cocci were the predominant causative group of pediatric UTI accounting for 52.45%. Whereas Gram negative bacilli were 47.54%. Enterococcus group was the predominant etiological agent for 45.90% with maximum resistance to Primary line of drugs like Penicillin G and Ampicillin.
Conclusion: Drug resistance pattern amongst urinary isolates of pediatric patients indicates that antibiotic selection should be based on knowledge of the local prevalence of bacterial organisms and antibiotic sensitivities rather than empirical treatment.

Keywords: Prevalence, Urinary isolates, Antimicrobial susceptibility, Pediatric patients, South Gujarat.

How to cite : Khandelwal N, Sutariya D, Retrospective study of bacteriological profile and their antibiotic sensitivity pattern in urine of pediatric patients (0-12 years) in a tertiary care hospital of South Gujarat. Indian J Microbiol Res 2020;7(4):373-376

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