Prevalence and antibiogram of Burkholderia species isolated from a tertiary care hospital

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Original Article

Author Details : Linju Joy*, Anita K B, Ashwin Chitrabanu N

Volume : 8, Issue : 1, Year : 2021

Article Page : 39-44

https://doi.org/10.18231/j.ijmr.2021.009

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Abstract

Background: The genus Burkholderia which was earlier considered as a soil saprophyte, is now gaining importance as a human pathogen. The pathogenic species include B. pseudomallei, B.cepacia, B.mallei, B.gladioli and B.thailandensis. Ongoing studies on Bukholderia spp. have resulted in the isolation of newer subspecies from human samples.

Aim: The study was undertaken to know the prevalence of Burkholderia spp among the clinical isolates in our hospital setup, to identify and also to evaluate their antibiogram.

Materials and Methods: Various clinical samples from patients were analysed along with their demographic data. All the specimens were processed according to the standard microbiology procedures.

Results: In a total of 4115 culture positive samples, 951 (23.11%) were identified as Non Fermenting Gram Negative Bacilli (NFGNB). 30 (3.2%) of these NFGNB were identified as Burkholderia spp. with an overall prevalence rate of 0.72%. 12 (40%) were further identified as B.pseudomallei and 18 (60%) as B.cepacia complex. 76.7% of the patients were above 40 years and a male preponderance was also observed (80%). Diabetes mellitus was found to be the major risk factor (60%) and fever was the commonest presentation (53.3%). Antibiotic sensitivity testing showed highest sensitivity to minocycline and cotrimoxazole and the least to imipenam.

Conclusion: This study provides a baseline data of the present scenario of Burkholderia infections in our hospital. A continuing study will be beneficial in identifying a number of cases as this is a grossly under-reported organism.

Keywords: NFGNB, Burkholderia infection, Risk factors, Prevalence, Antibiogram.

How to cite : Joy L , Anita K B, Ashwin Chitrabanu N, Prevalence and antibiogram of Burkholderia species isolated from a tertiary care hospital. Indian J Microbiol Res 2021;8(1):39-44

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