Study of seroprevalence of hepatitis a and e viruses in patients of acute viral hepatitis in a tertiary care centre in sub himalayan region

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Original Article

Author Details : Garima Sharma, Pallavi Sharma*, Amit Sharma, Santwana Verma, Prashant Panda, Gaurav Sharma

Volume : 9, Issue : 1, Year : 2022

Article Page : 24-27

https://doi.org/10.18231/j.ijmr.2022.004

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Abstract

Introduction: Acute viral hepatitis is a systemic infection affecting the liver predominantly. It is common health problem in areas where safe drinking water is not universally available. In recent times we have witnessed frequent outbreaks as a result of that.
Aim: To estimate sero-positivity of Hepatitis A and E viruses in indoor patients of hepatitis, presenting with jaundice using ELISA.
Settings and Design: Blood samples and clinical information were collected from cases of jaundice and referred to VRDL lab for analysis over a period of 1 year.
Materials and Methods : Samples were tested for anti –HAV immunoglobulin M (IgM) and anti –HEV immunoglobulin M (IgM).
Data was entered into a pre-structured data entry form, on Microsoft Excel sheet.
Results: The viral etiology was confirmed in 236 (41.1%) cases while in 337 (58.8%) cases no hepatitis virus could be detected, hepatitis E virus were found to be maximum in 45.76% cases, followed by HAV (39.83% cases)and while in 14.41% cases no hepatitis virus could be detected.
Conclusion: Routine basic microbiological analysis of drinking water should be carried out by assaying the presence of Escherichia coli by the multiple tube fermentation technique.
 

Keywords: Hepatitis, Jaundice, ELISA

How to cite : Sharma G, Sharma P, Sharma A, Verma S, Panda P, Sharma G, Study of seroprevalence of hepatitis a and e viruses in patients of acute viral hepatitis in a tertiary care centre in sub himalayan region. Indian J Microbiol Res 2022;9(1):24-27

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