Carbapenem resistant Acinetobacter baumannii in ICU patients in a tertiary care hospital: A retrospective study highlighting their demographic and clinical profile, impact on ICU stay and mortality

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Original Article

Author Details : Supriya Dey, Girish N*, Leela Rani, Ranjini , Rajendran

Volume : 10, Issue : 2, Year : 2023

Article Page : 96-100

https://doi.org/10.18231/j.ijmr.2023.017

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Abstract

Background: Acinetobacter baumannii was considered as a leading cause of nosocomial respiratory infection and bacteremia in many hospitals all over the world. However, there was a still a debates whether colonization and/or infection with Acinetobacter baumannii, increases morbidity and mortality independently of the effect of other risk factors..
Aim of the study was to isolate Acinetobacter baumannii among ICU patients, to detect carbapenem resistant Acinetobacter baumannii among ICU patients with Acinetobacter baumannii infections and to determine specific risk factors and outcome of the infections due to CRAB isolates.
Materials and Methods: A retrospective study was carried out at Vydehi Institute of Medical Sciences and RC in Bangalore, in the ICU department from June 2021 to May 2022.
Results: Among all the patients carbapenem resistance was detected more in patients above 60 years of age, males were predominant than females, most of the patients were on ventilation and in sepsis and mortality rate was high with the increased duration of ICU stays.
Conclusion: Acinetobacter baumannii is a highly prevalent microorganism among ICU patients, while its potential to acquire resistance toward commonly used antibiotics represents it as a grave threat to the health care industry. Therefore, signifying the need for its regular monitoring in the health care setups. VAP due to CRAB and excess use of intravascular devices are the most important risk factors for CRAB bacteremia in our ICU. Early implementation of appropriate antimicrobial therapy, particularly in critically ill ICU
patients with Carbapenem resistant Acinetobacter baumannii infections, with two or more co morbidities, can be crucial for survival.
 

Keywords: Carbapenem resistance, Acinetobacter baumannii, Multi drug resistance, Intensive care unit, Cardiac care unit, Cardiothorasic surgery unit, CRAB, VAP.

How to cite : Dey S, Girish N, Rani L, Ranjini, Rajendran, Carbapenem resistant Acinetobacter baumannii in ICU patients in a tertiary care hospital: A retrospective study highlighting their demographic and clinical profile, impact on ICU stay and mortality. Indian J Microbiol Res 2023;10(2):96-100

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