Bacteriological profile of bloodstream infections in pediatric age group in a tertiary care centre, Solapur

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Original Article

Author Details : Nilanjana Mukherjee, Prakash Hindurao Waghmare*, Deepak K Shinde, Vijaykumar V Chincholkar

Volume : 11, Issue : 2, Year : 2024

Article Page : 113-118

https://doi.org/10.18231/j.ijmr.2024.021

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Abstract

Background: Bloodstream infections (BSI) due to multidrug-resistant organisms from paediatric setup have become increasingly common. BSI can be transient and be rapidly cleared out by the host defence mechanism or be associated with high morbidity and mortality if it becomes persistent.
Materials and Methods: Blood samples were collected from 1112 children within a 1-year study period (July 2022 to June 2023) which included all children admitted with complaint of fever and suspected of having sepsis in Paediatric department of Shri Chhatrapati Shivaji Maharaj Sarvopchar Rugnalaya (SCSMSR), Solapur. Blood volume was collected depending upon age and body weight of the patient with aseptic precautions and inoculated in Brain Heart Infusion broth (BHI) which was incubated at 37°C for 7 days. Subcultures were made on blood agar and MacConkey agar plates. Organisms were identified by biochemical reactions and antibiotic susceptibility test of the isolates were performed by disk diffusion.
Results: Out of 1112 suspected cases, 175 (15.74%) were culture positive. Klebsiella species (27.43%) was the most common isolate followed by Acinetobacter species (16.57%). Most common Gram positive isolate was Staphylococcus aureus (11.43%) followed by Enterococcus spp. (6.86%). Total Multidrug resistant (MDR) isolates in Gram negative and Gram positive were 50.35% and 31.25% respectively.
Conclusion: High rates of antibiotic resistance are observed in both gram positive and gram negative organisms. Thus, there is an urgent need for proper implementation of antibiotic stewardship programme and infection prevention and control measures.

Keywords: Bloodstream infections, Paediatric, Antibiotic resistance, Blood culture.

How to cite : Mukherjee N, Waghmare P H, Shinde D K, Chincholkar V V, Bacteriological profile of bloodstream infections in pediatric age group in a tertiary care centre, Solapur. Indian J Microbiol Res 2024;11(2):113-118

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