Prevalence of Extended Spectrum Beta Lactamase amongst clinical specimens at a tertiary care hospital, Valsad


Original Article

Author Details : Drashti M Shah, Alka B. Nerurkar

Volume : 3, Issue : 3, Year : 2016

Article Page : 333-338


Suggest article by email

Get Permission

Abstract

Background: Extended Spectrum Beta Lactamase (ESBL) are a variant of β-lactamase enzymes that open the β- lactam ring thus inactivating the antibiotic and conferring resistance.
Objective:  To determine the prevalence of ESBL producing Gram Negative Bacilli isolated from various clinical specimens and to study their antibiotic susceptibility patterns.
Methodology: A cross sectional study was carried out at the Department of Microbiology, GMERS Medical College, Valsad for a period of 2 months. The antibiotic susceptibility patterns were tested using the Kirby- Bauer disc diffusion method following CLSI guidelines.
Results: 221 specimens were examined. Out of which 39 (18%) were Gram positive isolates, 63(28%) were Gram negative isolates and the rest 119 (54%) were no growth. Out of the 63 Gram Negative, 30(48%) were ESBL positive while the rest 33 (52%) were ESBL negative.
Conclusion: Prevalence of ESBL in Gram negative bacilli was 55% and thereby it sends a signal among the medical fraternity for the rational use of antibiotics.

Keywords: Antibiotic susceptibility testing, Bacterial resistance, Extended Spectrum Beta Lactamase, Gram Negative Bacilli


How to cite : Shah D M, Nerurkar A B, Prevalence of Extended Spectrum Beta Lactamase amongst clinical specimens at a tertiary care hospital, Valsad. Indian J Microbiol Res 2016;3(3):333-338


This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.







View Article

PDF File  


Copyright permission

Get article permission for commercial use

Downlaod

PDF File    






Article Access statistics

Viewed: 1408

PDF Downloaded: 482