Bacteriological profile and antimicrobial susceptibility pattern of clinical samples at a tertiary care centre

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Original Article

Author Details : Monika Rajani, Malay Banerjee

Volume : 4, Issue : 1, Year : 2017

Article Page : 31-35

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Abstract

Background: The occurrence of bacterial infections is a major cause of morbidity and mortality in patients. Inappropriate and irrational use of antibiotics has led to increasing resistance in commonly isolated gram positive and gram negative organisms. Antimicrobial resistance is a matter of concern as its compromises the management of infectious diseases and increases the cost of health care as well.
Aims and Objectives: This study was undertaken to document the common organisms isolated in patients in a variety of clinical conditions encountered and describe their antibiotic susceptibilities.
Materials and Methods: This retrospective study was conducted in Department of Microbiology at Career Institute of Medical Sciences and Hospital. The records of bacteriology section were compiled for a period of 6 months from January 2016 to June 2016. The results were consolidated for types of clinical samples, organisms isolated and their susceptibility patterns.
Results: Total 1121 samples were received in Department of Microbiology over a period of six months from January 2016 to June 2016 and 283(25.2%) were positive on culture. E coli, 38 (13.4%) was the predominant isolate followed by Staphylococcus aureus, 31(10.9%). The resistance pattern in E coli to Ceftazidime, Amoxicillin clavulanic acid and Imepenem was 30.3%, 22.9% and 14.7% respectively. Among S. aureus, 15.8%strains were Methicillin resistant.
Conclusions: Gram negative bacteria still remain the predominant causes in most of the clinical infections in health care settings with E coli being the most common organism in most of the cases. Antimicrobial resistance is a major challenge and antibiotics need to be tested and prescribed according to standard guidelines. Local anti-biograms should be available periodically to help clinicians guide on antibiotic prescribing.

Keywords: E coli, S. Aureus, Antimicrobial Resistance

How to cite : Rajani M, Banerjee M, Bacteriological profile and antimicrobial susceptibility pattern of clinical samples at a tertiary care centre. Indian J Microbiol Res 2017;4(1):31-35

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