Prevalence, bacteriological profile and antimicrobial resistance pattern of aerobic bacterial isolates from antenatal mothers with asymptomatic bacteriuria

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Original Article

Author Details : Shalima S, Kalaivani R, Seethesh G, Seetha KS

Volume : 4, Issue : 4, Year : 2017

Article Page : 419-423

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Abstract

Introduction: Urinary tract infections (UTI) in pregnancy are more common among antenatal women because of the physiological and morphological changes that occur during pregnancy. UTI may progress from asymptomatic to symptomatic bacteriuria as the pregnancy progresses. Asymptomatic bacteriuria (ASB) if not diagnosed earlier and treated properly, may lead to pyelonephritis, postpartum UTI, hypertensive disorders, prematurity, low birth weight babies and pre-natal death, etc.
Materials and Method: The present investigation was based on a total samples from 637 antenatal mothers with asymptomatic bacteriuria during August 2015 to October 2015. Their mid-stream clean catch urine was collected and was screened for asymptomatic bacteriuria by semi quantitative culture method. Isolates were identified and their antibiotic susceptibility testing was recorded.
Results: Out of 637 asymptomatic bacteriuria suspected antenatal women, 268 got reported as sterile, and the remaining 315 samples showed significant growth of single type of aerobic bacterial growth. Majority (66%) of these isolates were isolated from antenatal mother with age group between 21-35 years. Significant numbers of positive urine cultures were from antenatal women with third trimester of pregnancy with primigravidae. The proportion of asymptomatic bacteriuria in our study group was 49.5%. Gram negative bacilli were the predominant pathogen isolated, of which 56% were E.coli followed by others. All our Gram positive and Gram negative isolates showed very significant amount of resistance towards all the available group of drugs.
Conclusion: Though asymptomatic bacteriuria is more common during pregnancy, it needs early diagnosis with appropriate and adequate management. Thus the morbidity and mortality can be kept under control.

Keywords: Asymptomatic bacteriuria, Antenatal UTI, Significant bacteriuria, UTI in pregnancy

How to cite : Shalima S, Kalaivani R, Seethesh G, Seetha Ks, Prevalence, bacteriological profile and antimicrobial resistance pattern of aerobic bacterial isolates from antenatal mothers with asymptomatic bacteriuria. Indian J Microbiol Res 2017;4(4):419-423

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