Speciation and antibiogram of Staphylococcus isolated in a tertiary care centre

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Original Article

Author Details : Neelesh Naik, Anusuya Devi D*, Veena Krishnamurthy

Volume : 5, Issue : 3, Year : 2018

Article Page : 404-407

https://doi.org/10.18231/2394-5478.2018.0084

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Abstract

Introduction: Staphylococcus have become common cause of skin and soft tissue infections. Resistance to a number of drugs have increased and methicillin resistant Staphylococcus aureus (MRSA) and inducible clindamycin resistance (iMLS_B) have become a major problem for the treatment of Staphylococcal infections. This study was undertaken to detect MRSA and iMLS_B and to determine the antibiotic susceptibility pattern of the isolates.
Materials and Methods: 150 isolates of Staphylococcus were studied for detecting the antibiotic resistance pattern and also to detect MRSA using cefoxitin disc and oxacillin E test. iMLS_B resistance among MRSA strains was detected using D test.
Results: Out of 150 isolates of Staphylococcus, 117(78%) isolates were of Staphylococcus aureus and 33(22%) isolates were of Coagulase negative Staphylococci. Staphylococcus was most sensitive to vancomycin followed by linezolid and clindamycin. Penicillin was the least sensitive antibiotic. 29 (24.7%) strains of Staphylococcus aureus were MRSA. Among them, 16(44.8%) were erythromycin resistant and 4(13.7%) of erythromycin resistant strains were found to be inducible clindamycin resistant.
Conclusion: Testing of all the isolates of Staphylococcus for antibiotic resistance and to test Staphylococcus aureus for MRSA and for iMLS_B resistance is important in determining the antibiotic sensitivity which will prevent treatment failure.

Keywords: Antibiogram, Methicillin resistant Staphylococcus aureus, Inducible clindamycin resistance.

How to cite : Naik N, Anusuya Devi D, Krishnamurthy V, Speciation and antibiogram of Staphylococcus isolated in a tertiary care centre. Indian J Microbiol Res 2018;5(3):404-407

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