Indian Journal of Microbiology Research

Official Publication of Innovative Education and Scientific Research Foundation


Volume 12, Issue 3, Year 2025, No of articles 21
Editorial
Fungal infections: The ignored threat requiring a global response
Author details: Anand Bhimaray Janagond, Amith Joshi
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Review Article
Global and Indian distribution of hepatitis B virus (HBV) genotypes/sub-genotypes 
Author details: Vivek Gaur, Ajay Singh, Amresh Kumar Singh, Sushil Kumar, Ankur Kumar, Nandini Singh
Hepatitis B virus (HBV) infection is a serious global public health concern in the modern era. It was estimated around 2 billion individuals throughout world are affected with HBV and 350 million of them suffers from a chronic infection. India is the most broadly diversified nation in identity and s....
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The impact of educational interventions in improving safety practices of healthcare workers: A systematic review
Author details: Garba Jamiu Olalekan, Nahlah Abduljaleel Alsaidi
Background: Healthcare workers encounter a variety of occupational hazards that predispose them to accidents and are at a high risk of exposure to bloodborne infection while carrying out their duties. The prevalence of exposures to highly infectious agents has further intensified the need to take oc....
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Monkeypox transmission and control strategies in the modern era
Author details: Shakthivel C D, Janane Murugesan, Gokulavasa Nagarajan, Alaimagal Ravi, Bhoopalan Shanmugam, Aruna Palanisamy
Monkeypox is a viral infection caused by a double-stranded DNA virus, a member of poxviridae family and the Orthopoxvirus genus. It was first discovered in monkeys in 1958.1970 marked the first human case of monkeypox, and 2022 marked the outbreak. Several countries in central and western Africa hav....
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Regenerative medicine in India: A landscape review of scientific progress, regulatory pathways, and future opportunities
Author details: Rakesh Pandit, Ashutosh Shukla, Nikita Paliya
India stands at a unique and pivotal crossroads in the global landscape of regenerative medicine. With its vast patient population, skilled scientific workforce, and burgeoning biotechnology sector, the nation holds immense potential to become a leader in this revolutionary field. This comprehensive....
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Original Article
Efficacy of plant-derived extracts against multidrug resistant pathogens: A potential alternative to conventional antibiotic therapy
Author details: Oviya Priya I, Priyadarshini Shanmugam, Ankush Chauhan, Alice Peace Selvabai
Background: Antimicrobial resistance (AMR) poses a global threat and reported as a leading cause for morbidity and mortality. It is mediated by several factors like irrational use of antibiotics for treatment in various diseases, the misuse of antibiotics, especially in livestocks, improper hygiene....
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Training interns with a structured pathology and microbiology module during elective posting of compulsory rotating medical internship
Author details: Asitava Deb Roy, Veena Jyoti, Aarushi Khajuria, Mala Mukherjee, Dipmala Das, Himel Mondal
Background: Pathology and microbiology are essential for clinical decision-making, yet medical interns often receive minimal structured training in these areas. In India, the National Medical Commission (NMC) mandates laboratory medicine exposure during internship, but implementation varies. This st....
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Predictive analysis of binding affinity among human cytomegalovirus (HCMV) proteins and class-I major histocompatibility complex (MHC-I) molecules
Author details: Balaka Biswas, Ankita Bhaduri, Mousumi Saha, Dipanwita Das, Agniswar Sarkar
Background: Human Cytomegalovirus (HCMV) is a widespread herpesvirus that establishes persistent infections by evading host immune surveillance. A critical strategy involves the disruption of antigen presentation via Class I Major Histocompatibility Complex (MHC-I) molecules, thereby impairing cytot....
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Ticking the clock: Modified Kirby-Bauer’s technique for accelerated antibiotic susceptibility reporting 
Author details: R Gowtham, Sowmya G Shivappa, Rashmi P Mahale, Morubagal Raghavendra Rao, Sulochanadevi B C, Ranjitha Shankare Gowda, Vidyavathi B Chithragi, Neetha S Murthy
Background: Antibiotic resistance poses a global health threat, potentially leading to a post-antibiotic era with severe consequences. Timely and accurate antimicrobial susceptibility testing (AST) is critical for effective treatment, reducing mortality, and combating antimicrobial resistance (AMR).....
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Phenotypic detection of virulence attributes in MDR Acinetobacter from a tertiary care hospital, South India
Author details: Monisha Basavaraju, Rashmi P Mahale, M Raghavendra Rao, Suchitra Shenoy
Background: The nosocomial pathogen Acinetobacter baumannii is found all over the world and has a number of virulence characteristics that enable them to render resistance to antibiotics, making them multidrug resistant.Objectives: To detect the virulence attributes of MDR Acinetobacter baumannii is....
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Evaluation of polyester polyurethane-degrading capability of bacteria isolated from landfill sites
Author details: Xuan Ngoc Thanh Nguyen, Nguyen Nu Thao Lu, Tham Van Hong Vo, Hai Ngoc Nguyen
Background: Polyurethane (PU) is one of the most widely used categories of plastics in modern life. The enormous demand for PU has contributed to the global plastic crisis. In recent years, microbial strains capable of degrading plastics have garnered significant scientific interest. In the study, b....
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Clinico-mycological profile and antifungal susceptibility patterns of zygomycosis during the COVID-19 pandemic at a tertiary care center
Author details: Sinduja Subramaniyan, Anupma Jyoti Kindo, Prasanna Kumar Saravanam
Background: Zygomycosis has emerged as a significant opportunistic fungal infection, with a marked increase in incidence during the COVID-19 pandemic, particularly among immunocompromised individuals such as those with diabetes mellitus.Aim: To analyze the clinico-mycological profile of zygomycosis....
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Correlation of antimicrobial resistance, biofilm production of bacteria infecting grade 2 and 3 diabetic foot ulcers
Author details: MasoodAhmed Tahashildar, Sheetal Harakuni, Shrishail Metgud, Basavaraj M Kajagar, Manoj Togale
Background: Diabetes is a notorious metabolic disorder characterized by long-term complications such as chronic diabetic foot ulcers (DFUs). DFUs pathogenesis is a product of complex factors lead by long-term diabetic mellitus. The ulcers usually get infected and make treatment complicated.Objective....
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Xpert carba R assay for carbapenem resistant gram-negative bacterial blood culture isolates: An experience at a tertiary care hospital
Author details: Prasanna N Bhat, Kavitha Prabhu, Anup Kumar Shetty, Ganesh Nayak S
Background: Carbapenem resistant blood stream infections are a serious threat to provision of effective and affordable healthcare to the patients. It is important to determine the mechanism of the resistance, so that the appropriate treatment can be provided to the patient. The study aims to evaluat....
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An interventional study to assess improvement in knowledge attitude and practice on antimicrobial use and resistance among rural community in Tamil Nadu, India
Author details: Sujin Padmanabhan, Valarmathi Balakrishnan, Savitha Govindarajan, Saranya Loganathan Kumaresan, Sendilkumar Balasundaram, Gayathri Kumar
Background: In rural Indian communities, misuse of antibiotics contributes significantly to rising antimicrobial resistance (AMR). A village in South India was chosen as it represents a typical setting where patterns of antibiotic use remain suboptimal due to low awareness and improper access.Aim an....
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Emergence of metronidazole and clindamycin resistance among anaerobic Bacteroides fragilis group - A study from South India
Author details: Sandra Jacob, Supriya Gachinmath
Background: Bacteroides fragilis is the most common pathogenic group among anaerobic pathogens, primarily causing infections such as deep visceral abscesses, brain abscesses, diabetic foot ulcers, etc. Recent studies have shown increasing resistance among these bacteria to common antibiotics like me....
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Comparative evaluation of the microbial load and dimensional accuracy of dental impressions disinfected with immersion under 2% glutaraldehyde and 0.5% sodium hypochlorite: An ex vivo study
Author details: Aishwarya Ramasubramanian, Mridula Joshi, Minakshi Bhattacharjee, Ashwini Panchmahalkar, Swapnali Mhatre, Mahesh Ghadage, Nilesh Joshi, Sanpreet Singh Sachdev
Background: Dental impressions are potential vectors for cross-infection due to contamination with saliva and blood. Effective disinfection is critical to prevent transmission of pathogens without compromising the dimensional accuracy of the impressions. This study aimed to evaluate and compare the....
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Genetic analysis of virulence factors of MDR Klebsiella pneumoniae spp. pneumoniae isolated from clinical specimens - study from a tertiary care hospital
Author details: Bhavita Thakorbhai Prajapati, Anant Prabhakar Marathe, Asmabanu Mahammed Hanif Shaikh, Shital Sangani
Background: Klebsiella pneumoniae is a predominant nosocomial pathogen owing to its potent virulence factors, viz, capsule, fimbriae, siderophores, efflux pump, regulatory secretions, and secretory system. As most nosocomial K. pneumoniae infections are MDR/XDR, treatment remains limited. The unders....
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Hidden burden: Hepatitis C virus infection among multi-transfused thalassemic children in Gujarat
Author details: Saurabh Chhotalal Norris, Pankti C Pargi, Binda Prakashbhai Pipaliya, Rachana Dhirubhai Patel, Tanuja Bakul Javadekar
Background: Thalassemia is a genetic hemoglobinopathy leading to chronic anemia, frequently requiring regular blood transfusions. Recurrent transfusions elevate the risk of transfusion-transmitted infections (TTIs), including hepatitis B virus (HBV), hepatitis C virus (HCV), HIV, and syphilis. Iron....
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Case Series
Unveiling the menace: a case series of fungal meningitis with galactomannan and beta-D-glucan detection and the efficacy of amphotericin B and flucytosine treatment
Author details: Rachana Patel, Bhavinkumar Bhagubhai Patel, Trupti Jansari, Amit Pravin Chauhan, Tanuja Javadekar
Fungal meningitis is a rare but serious infection of the central nervous system with high morbidity and mortality, especially when diagnosis is delayed. Standard CSF analysis often fails to identify the aetiology, making early detection challenging. This case series explores the utility of CSF funga....
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Case Report
Fatal cryptococcal meningitis in a patient with uncontrolled diabetes mellitus: A case report
Author details: Sumana Mahadevaiah Neelambike, Neetha S Murthy, Sowmya G Shivappa, R Gowtham
Cryptococcal meningitis (CM) is an opportunistic yeast infection which necessitates prudent diagnostic & treatment protocols. This opportunistic fungus is universal in distribution and acquired through inhalation. Literature highlights the association of CM with deficient T- cell mediated immuni....
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